National Academy of Sciences of Belarus

SLOBOZHANINA Ekaterina Ivanovna

Ekaterina Ivanovna Slobozhanina (b. 10.03.1945, Lelchitsy, Gomel region), a scientist in the field of photobiology and membrane biophysics. Corresponding Member of the National Academy of Sciences of Belarus (2000), Doctor of Biological Sciences (1992), Professor (2003).

Investigated the relationship of photonics and structural dynamics of protein macromolecules in solution and in the composition of biological membranes. She conducted a comparative study of the sensitivity of various parameters of intrinsic and probe fluorescence to changes in the structural state of proteins when exposed to biologically active substances. Established the patterns of modification of the structural-functional state of biological membranes under the action of physicochemical factors of different nature and specificity on them, the relationship between structural changes in erythrocyte membranes, metabolic shifts and the development of pathological processes in the body. Proved the applicability of fluorescent methods to identify features of the structural state of proteins in biomembranes in pathology, which was the basis for the wide use of luminescence in biomedical research. Developed a number of rapid methods of photodiagnostics of diseases.

Author of more than 300 scientific papers, incl. 1 monograph, 7 inventions.

State Prize of the Republic of Belarus in 1992 for the series of works "Luminescence of proteins and its use in scientific research and in practice".

Major papers:

  1. Спектральный люминесцентный анализ в медицине. Минск: Наука и техника, 1989 (совм. с Е.А. Черницким).
  2. Окисление мембранных белков и изменение поверхностных свойств эритроцитов (в соавт.) // Биофизика. 1998. Т. 43, вып.3.
  3. Flavonoide treatment of human erythrocytes protects membrane-bound NADH-methemoglobin reductase against oxidative damage (в соавт.) // Current Topics in Biophysics. 2000. Vol. 24(2).
  4. Эриптоз – запрограммированная гибель эритроцитов // Успехи современной биологии. 2014. Т. 134, № 2. С. 149–157. (совм. с Е.И. Белевич, Д.Г. Костиным).
  5. Активность флиппазы в эритроцитах человека при изменении структурного состояния белков цитоскелета // Новости медико-биологических наук. 2016. Т. 13, №1. (совм. с Е.И. Белевич, Д.Г. Костиным).
  6. Сравнительное исследование изменений структурно-функционального состояния мембран эритроцитов при воздействии амилоидов in vitro и у пациентов с сахарным диабетом II типа (в соавт.) // Новости медико-биологических наук. 2017. Т. 15, №1. С. 20–24.