National Academy of Sciences of Belarus

VISMONT Frantishek Ivanovich

Frantishek Ivanovich Vismont (b. 12.06.1950, Lida, Grodno region), a scientist in the field of physiology and pathology. Corresponding Member of the National Academy of Sciences of Belarus (2004), Doctor of Medical Sciences (1990), Professor (1997).

Work in the field of pathological mechanisms in the protective and adaptive reactions of the body. The role of endotoxemia in physiology and pathology, in the occurrence of dysregulation pathology has been elucidated, the mechanisms of violation and maintenance of systemic functions of the body, temperature homeostasis, thermal resistance in the occurrence of pre-pathological and pathological conditions, in the pathogenesis of hyperthermia and febrile conditions have been studied. The regulatory and pathogenetic role of the system of organic proteolysis and endogenous protease inhibitors in the central mechanisms of body temperature regulation has been proven. The value of the brain's reninangeotensin system, endogenous proteinase inhibitors, in the mechanisms of development of febrile conditions has been experimentally established. It has been established that an increase in the activity of alpha-antitrypsin in the blood is an important pathogenetic factor of endotoxin fever. He showed a close relationship between the functional activity of the thermoregulatory structures of the brain and the level in the blood of endogenous inhibitors of proteases synthesized by hepatocytes. The regulatory role of hepatocytes and Kupffer cells, their detoxification and endotoxin-neutralizing functions in the mechanisms of formation of the thyroid status of the body and the regulation of body temperature have been elucidated.

Author of more than 260 scientific papers, incl. 2 monographs, 3 textbooks and 2 inventions.

Awarded with the Medal of Francisk Skaryna (2007).

Major papers:

  1. Об участии пептидгидропаз мозга в центральных механизмах терморегуляции при перегревании и пирогеналовой лихорадке // Нейрогиптиды и терморегуляция. Мн., 1990.
  2. Роль ренинангиотензиновой системы мозга в центральных механизмах терморегуляции при пирогеналовой лихорадке // Термофизиология. Мн., 1994. Вып.3.
  3. Хроничекие поражения печени холестатической и токсической природы. Мн.: БДМУ, 2004 (в соавт.).
  4. Зависимость терморегуляции от состояния детоксикационной функции печени и выраженности эндотосинемии // Нейрогуморальные механизмы регуляции функции в норме и патологии. Мн., 2007.
  5. Патологическая анатомия и патологическая физиология. Мн.: Вышэйшая школа, 2007 (в соавт.).
  6. Основы биоэтики. Мн.: Вышэйшая школа, 2010 (в соавт.).